Shortly after entering Anankis' Hall 1, before the first miniboss fight, shortly before the first sighting of Primordial Guardians, there is a very small golden-portal side area containing a cursed chest. This side area has no exit. Whether completed or failed, the only way out is to town-portal out and then waystone back to Anankis' Hall.

A little beyond that, there is a LARGE split in the path, the right branch going up a flight of stairs. You can walk around the long way to the top of this flight of stairs, but you cannot walk up or down it from either side; the bottom half of the staircase is simply impassable even though nothing visible is blocking it.