I have definitely noticed issues with champions and bosses doing attacks but facing the wrong direction (mostly Alpha Sviirs charging while facing the wrong direction). I have also noticed some sort of lag during boss fights where the boss does a skill where I just was and have since moved, but it still hits or grabs me anyway (namely with Demon of Flesh, but sometimes Devourer or Demon of Souls). Sometimes it even happens during an active dodge, when I thought I wasn't supposed to be able to be hit.

I know for a fact that it isn't my internet, though I must admit, I am using an older PC (and thus have graphical settings turned ALL the way down, though the game still visually looks amazing). It seems to be about .5 seconds (500 ms) of lag.