1. Ranged misses 80%+ of the time, sometimes moving fixes this most of the time it does not. both basic attacks and skills miss, and it appears to be worse in act3
2. Buffs and Debuffs either are not working/applying or do not show at all. I used to see little boxes with numbers telling me ailments and status effects, but now there is nothing. I have no clue if i am applying ailments or if any buffs/debuffs are on me or the enemies.
3. selling things becomes troublesome and sometimes the game confuses left click and right click and the whole thing becomes time consuming taking 3x longer than it should.
4. zone changing sometimes does not work properly and i get stuck at a border area unable to enter new zone or move in the current loaded zone.

I so far have only played with a spell caster/Ranged/Hybrid so i dont know if these things apply to melee characters, but would like to know if they do.
I know i am currently forgetting some of the problems i have noticed, but if anyone else has additions or answers/solutions to any of these issues please feel free to add them. Thanks for reading.