I've been having the same issue.

Exactly the same here. Additionally, the game doesn't save the progress for the waypoint in this cave. True drama - the game has more serious bugs than right after its premiere .....

Anyone know if a fix for this, took me one whole day to finish the first boss in the cave because of this bug had to run all the way to him and not kill anything for fear of hitting a box. It did work, now im stuck in the area after the necropolis, hit ice crash, hit box crash, so i ran to the first guardian boss with out killing anything, got him to half health and BAM crash. It took me 4 hours just to get to him >.>

Other than avoiding the destroyables, I do not know of a fix atm. But ignoring the destoryables let me continue on to the boss in the den, so I'm assuming it will do the same to the latter.

Unfortunate considering as a caster, your main willpower generator has a high chance to ricochet into destroyables very easy...

Seems to be very common upon entering the "dens" of the hunt boss. At least that's the two times it's happened to me. Elsewhere shows no effect on smashing destroyables.

Caster is virtually unplayable with these conditions.