For people that play seasonal content, the chronicles, that won't be so bad because they have to go through the campaign again anyway.
In regards to colours, i could swear i have unlocked some colours twice or thrice in my current playthrough but it could be supersticion, didn't pay enough attention when it happened. Feels fishy. If i can get my hands on more colour drops, i will run some tests.
Edit: Indeed, there are colours that can be consumed after already unlocking them. Will open a separate thread for that Bug.